Sepsis is a life-threatening illness caused by the body’s overreaction to an infection and can be triggered either directly by infection or may occur after medical treatment or surgery. The mortality rate in patients admitted to hospital with severe sepsis is 28-50% and it remains the most prevalent cause of death in non-coronary Intensive Care Units (ICUs ). It has been estimated that in the US ~$17 billion is spent annually treating sepsis in patients and that a similar amount is spent across the EU. To reduce costs and provide better treatment to patients, early, accurate diagnosis is critically important.
The CE-microArray project will utilise existing technology from clinical chemistry, microplate readers and cavity enhanced spectroscopy in a truly novel way to develop more sensitive, accurate, faster and more useful diagnostic platform. The project consortium comprises experienced SMEs from across Europe, who are interested in undertaking the required Research and Development to produce working prototypes in preparation for commercialisation, and R&D specialists who will work to realise this goal. The project aims to produce a solution based on colorimetric detection that will be up to 100 times more sensitive than those currently available, reducing the damage to patients with sepsis, and allowing sensitive and accurate detection of an increased range of biomarkers at lower cost and higher throughput.